Los estudios sobre el perfil de los aspirantes a la educación superior son escasos. Se compararon cuantitativamente características familiares, socioeconómicas y académicas de los aspirantes a la Licenciatura en Educación Primaria de las escuelas normales públicas de Baja California y Puebla. Perfil: mujer, soltera, 18 años, egresada de bachillerato general escolarizado. Se identificaron características más favorables en Baja California.

To survive and be successful in today's setting of globalisation and complexity, companies are obliged to think in wider strategic terms, developing active and enterprising strategies that include social, political and ecological elements, besides the economic ones. The analysis of the relationship between companies and society is especially interesting when these companies operate in international markets. Countries demand that large corporations contribute to local, regional and national development in such a way that their resources are exchanged for a significant increase (...) in their citizens' quality of life. Faced with that fact, the aim of this work is to establish what actions the subsidiaries will take in order to offer a response to the needs of their stakeholders in the host countries. Secondly, we attempt to identify the factors explaining the different levels of social response of the subsidiaries established in a particular country by different parent companies. The empirical study was carried out on a sample of Spanish subsidiaries in the two manufacturing industries with most foreign investment (the chemical and automobile industries) and the results obtained both confirmed the validity of the tool used to measure social response and permitted us to determine which factors influence the institutionalisation of social responsiveness. (shrink)

To survive and be successful in today's setting of globalisation and complexity, companies are obliged to think in wider strategic terms, developing active and enterprising strategies that include social, political and ecological elements, besides the economic ones. The analysis of the relationship between companies and society is especially interesting when these companies operate in international markets. Countries demand that large corporations contribute to local, regional and national development in such a way that their resources are exchanged for a significant increase (...) in their citizens' quality of life. Faced with that fact, the aim of this work is to establish what actions the subsidiaries will take in order to offer a response to the needs of their stakeholders in the host countries. Secondly, we attempt to identify the factors explaining the different levels of social response of the subsidiaries established in a particular country by different parent companies. The empirical study was carried out on a sample of Spanish subsidiaries in the two manufacturing industries with most foreign investment (the chemical and automobile industries) and the results obtained both confirmed the validity of the tool used to measure social response and permitted us to determine which factors influence the institutionalisation of social responsiveness. (shrink)

ABSTRACTPrior research has found a relationship between perceived facial attractiveness and perceived personal trustworthiness. We examined the time course of attractiveness relative to trustworthiness evaluation of emotional and neutral faces. This served to explore whether attractiveness might be used as an easily accessible cue and a quick shortcut for judging trustworthiness. Detection thresholds and judgment latencies as a function of expressive intensity were measured. Significant correlations between attractiveness and trustworthiness consistently held for six emotional expressions at four intensities, and neutral (...) faces. Importantly, perceived attractiveness preceded perceived trustworthiness, with lower detection thresholds and shorter decision latencies. This reveals a time course advantage for attractiveness, and suggests that earlier attractiveness impressions could bias trustworthiness inferences. A heuristic cognitive mechanism is hypothesised to ease processing demands by relying on simple a... (shrink)

I provide a variation on ideas presented by Walton and Currie, elaborating the view that fictive utterances are characterized by a specific form of illocutionary force in the family of directives – a proposal or invitation to imagine. I make some points on the relation between the proposal and the current debates on intentionalist and conventionalist views, and I discuss interesting recent objections made by Stacie Friend to the related, but crucially different, Gricean view of such force advanced by Currie (...) and others. (shrink)

María Lugones was a feminist philosopher whose work spanned four decades, two continents, and multiple languages. Over the course of her career, her writing made major contributions to feminist ethics, the philosophy of race, lesbian epistemology, and decolonial thought. She passed away on July 14, 2020, after many years of poor health, leaving behind an influential legacy and a substantial body of unpublished work.

Although the interdisciplinary nature of contemporary biological sciences has been addressed by philosophers, historians, and sociologists of science, the different ways in which engineering concepts and methods have been applied in biology have been somewhat neglected. We examine - using the mechanistic philosophy of science as an analytic springboard - the transfer of network methods from engineering to biology through the cases of two biology laboratories operating at the California Institute of Technology. The two laboratories study gene regulatory networks, but (...) in remarkably different ways. The research strategy of the Davidson lab fits squarely into the traditional mechanist philosophy in its aim to decompose and reconstruct, in detail, gene regulatory networks of a chosen model organism. In contrast, the Elowitz lab constructs minimal models that do not attempt to represent any particular naturally evolved genetic circuits. Instead, it studies the principles of gene regulation through a template-based approach that is applicable to any kinds of networks, whether biological or not. We call for the mechanists to consider whether the latter approach can be accommodated by the mechanistic approach, and what kinds of modifications it would imply for the mechanistic paradigm of explanation, if it were to address modelling more generally. (shrink)

The origin of the eukaryotic cell nucleus and the selective forces that drove its evolution remain unknown and are a matter of controversy. Autogenous models state that both the nucleus and endoplasmic reticulum (ER) derived from the invagination of the plasma membrane, but most of them do not advance clear selective forces for this process. Alternative models proposing an endosymbiotic origin of the nucleus fail to provide a pathway fully compatible with our knowledge of cell biology. We propose here an (...) evolutionary scenario that reconciles both an ancestral endosymbiotic origin of the eukaryotic nucleus (endosymbiosis of a methanogenic archaeon within a fermentative myxobacterium) with an autogenous generation of the contemporary nuclear membrane and ER from the bacterial membrane. We specifically state two selective forces that operated sequentially during its evolution: (1) metabolic compartmentation to avoid deleterious co‐existence of anabolic (autotrophic synthesis by the methanogen) and catabolic (fermentation by the myxobacterium) pathways in the cell, and (2) avoidance of aberrant protein synthesis due to intron spreading in the ancient archaeal genome following mitochondrial acquisition and loss of methanogenesis. BioEssays 28: 525–533, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

This paper will concentrate mainly on the analysis of some features present in Putnam's internal realism and in his "natural realism" that he shares with the pragmatist thinkers Peirce and James. Following the middle way which Putnam tries to reach between "reactionary metaphysics" and "irresponsible relativism," the first part of the paper deals with what is the positive insight of traditional realism, i. e., the reality of external things as independent from our mind, as it is emphasized by Putnam. It (...) also analyzes how this idea of the mind-independent character of reality has been very well worked out in Peirce's thought through the category of Secondness. The second part focuses on the right insight of relativism that Putnam wants to maintain: How our notion of reality changes and evolves together with our language, our life and our handling the world. The attention that H. Putnam pays to W. James is, also, especially important in relation to his way of understanding reality. (shrink)

The idea that natural selection acts on many levels—and not only at the level of organisms or individual genes—is increasingly accepted among biologists. However, it is not easy to reconcile this idea with the strictly “individualistic” conception of the evolutionary process that has always characterized Darwinian thought. Moreover, the individuality of some forms of life is a vague concept and therefore controversial. This is the case of Candidatus Magnetoglobus multicellularis, whose discovery immediately inspired the following question: Does the concept of (...) individuality have degrees? Alternatively, how far is this structure of prokaryotic cells from deserving to be called an organism? In this article, we propose a new conceptual scheme based on an idea of individuality that is not limited to organisms and that makes sense in terms of Darwinian evolution. In this conceptual scheme, selection at levels above that of the individual organism is interpreted as the evolutionary emergence of higher-level individuality. This proposal may serve as a basis on which to construct a promising hierarchical evolutionary theory. (shrink)

Este artigo apresenta uma revisão de literatura, que possui como objetivo investigar como o fenômeno corpolatria está inserido em publicações científicas. Teve como lócus três portais de buscas (Scielo, Portal de Periódicos da CAPES e Google Acadêmico) e recorte temporal de 2012 a 2021. Os dados foram analisados qualitativamente, no qual, averiguou-se a conceituação de corpolatria destacada na literatura e o local de origem dos estudos. A partir dos resultados, inferiu-se que a temática ainda é incipiente entre os pesquisadores brasileiros, (...) embora haja boa distribuição geográfica dos estudos. Percebeu-se que corpolatria é uma patologia da modernidade, caracterizada pelo culto exagerado do corpo, referendada como uma espécie de ditadura corporal, estabelecida pelo discurso do corpo perfeito. Disseminada pela mídia, pelas redes sociais e pela sociedade, caracteriza-se como uma patologia social à medida que causa mal-estar social, pois pode gerar consequências físicas, transtornos psicológicos e insegurança. (shrink)

Drawing on Husserl, Ingarden and Levinas’ works, this article explores Ibsen’s Rosmersholm from a phenomenological perspective, aiming to shed light both on this play and on the phenomenology of hunger and theatre, as well as on the larger meaning of alimentary enjoyment.

Fred Sanger, the inventor of the first protein, RNA and DNA sequencing methods, has traditionally been seen as a technical scientist, engaged in laboratory bench work and not interested at all in intellectual debates in biology. In his autobiography and commentaries by fellow researchers, he is portrayed as having a trajectory exclusively dependent on technological progress. The scarce historical scholarship on Sanger partially challenges these accounts by highlighting the importance of professional contacts, institutional and disciplinary moves in his career, spanning (...) from 1940 to 1983. This paper will complement such literature by focusing, for the first time, on the transition of Sanger’s sequencing strategies from degrading to copying the target molecule, which occurred in the late 1960s as he was shifting from protein and RNA to DNA sequencing, shortly after his move from the Department of Biochemistry to the Laboratory of Molecular Biology, both based in Cambridge (UK). Through a reinterpretation of Sanger’s papers and retrospective accounts and a pioneering investigation of his laboratory notebooks, I will claim that sequencing shifted from the working procedures of organic chemistry to those of the emergent molecular biology. I will also argue that sequencing deserves a history in its own right as a practice and not as a technique subordinated to the development of molecular biology or genomics. My proposed history of sequencing leads to a reappraisal of current STS debates on bioinformatics, biotechnology and biomedicine. (shrink)

The rapid urbanization of modern cities necessitates innovative approaches to data collection and integration for smarter urban management. With the Internet of Things (IoT) at the core of these advancements, the ability to efficiently gather, analyze, and utilize data becomes paramount. Generative Artificial Intelligence (AI) is revolutionizing data collection by enabling intelligent synthesis, anomaly detection, and real-time decision-making across interconnected systems. This paper explores how generative AI enhances IoT-driven data collection in smart cities, focusing on applications in transportation, energy, public (...) safety, and environmental monitoring. By addressing challenges such as data privacy, scalability, and ethical considerations, the study highlights how generative AI transforms urban governance and paves the way for sustainable and citizen-centric development. Key trends, case studies, and future research directions are discussed, showcasing the potential of generative AI as a cornerstone of smart city initiatives. (shrink)

Given the potential that environmentally oriented anti-consumption (EOA) has in achieving environmental sustainability, the authors draw upon marketing, management, environmental, and psychology studies to conceptualize and delimit EOA, differentiating it from other (related but distinct) phenomena. In addition, the authors review the available literature at the individual (micro) level and summarize research on the antecedents and meanings of broad and specific/strict EOA practices with different targets. Furthermore, the authors propose an agenda for future research, which reflects on EOA not only (...) at the individual (micro) level, but also lays out new opportunities for EOA work at organizational (meso), industry, and national (macro) levels. The work presented here hopes to spark multilevel research on EOA, its antecedents and consequences, and reactions to EOA phenomena. (shrink)

An ordering (≤K) on maximal almost disjoint (MAD) families closely related to destructibility of MAD families by forcing is introduced and studied. It is shown that the order has antichains of size.

Este artículo pretende establecer los nexos y asociaciones de los conceptos fundamentales que sustentan la obra filosófica, pero sobre todo la critica literaria de Rafael Gutiérrez Girardot. Hegel y Schlegel aparecen como pilares que fundamentan sus interpretaciones criticas y sobre los cuales se abre el horizonte de América Latina; a través de autores como Jorge Luis Borges, Alfonso Reyes y César Vallejo.

Urban resilience is critical for ensuring the sustainability and adaptability of cities in the face of growing challenges such as climate change, population growth, and infrastructure degradation. Predictive analytics, powered by Artificial Intelligence (AI) and the Internet of Things (IoT), offers a transformative approach to enhancing urban resilience. This paper explores how AI-driven predictive analytics can optimize disaster preparedness, infrastructure maintenance, and resource allocation in smart cities. By integrating real-time data from IoT sensors with advanced machine learning models, cities can (...) proactively address vulnerabilities and improve decision-making. This study highlights key applications, challenges, and future directions for leveraging predictive analytics to build resilient urban ecosystems. (shrink)

Background: The first wave of the COVID-19 pandemic caused a shortage of qualified nurses in Spain. As a result, the government authorized the hiring of senior students. Objectives: To explore the ethical dilemmas and ethical conflicts experienced by final-year nursing students who worked during the first outbreak of the COVID-19 pandemic in Spain. Research design: A qualitative exploratory study was conducted using purposive sampling. Semi-structured interviews were carried out using a question guide. Interviews took place via a private video chat (...) room platform. A thematic, inductive analysis was performed of the information gathered. Participants and research context: Eighteen nursing students were recruited from two universities of Madrid, aged between 18 and 65 years old, enrolled in the fourth year of nursing studies and who were hired under a relief contract for health professionals during the pandemic. Ethical considerations: The present study was carried out in accordance with the Declaration of Helsinki, and the study was approved by the Local Ethics Committee of Universidad Rey Juan Carlos. Results: Three specific themes emerged: (a) coping with patient triage, (b) difficulties in providing end-of-life care, and (c) coping with patient death. Nursing students participated in the process of patient selection for resource allocation and ICU bed occupancy. They were shown how to care for patients who were not admitted to the ICU, in their last moments and were faced with the difficulties of applying end-of-life care. Finally, the nursing students were confronted with the death of their patients, in overwhelming numbers and under adverse conditions. Conclusions: These findings can help shed light on the ethical dilemmas and ethical conflicts faced by novice nursing students, incorporated into the workforce during the COVID-19 pandemic. Moreover, it was described that students may normalize the death due to the exhaustion and overwhelmed routine. (shrink)

Este artículo muestra los paralelismos y las divergencias del giro ontológico y de la antropología fenomenológica. Ambas corrientes, en fidelidad al dato etnográfico, comparten el rechazo al régimen de representación y ambas corrientes cuestionan los compromisos epistémicos del investigador. Sin embargo, el giro ontológico presenta una orientación conceptual, que deriva a menudo en tipología, mientras que la antropología fenomenológica atiende a las relaciones perceptivas del mundo de la vida desde una apertura hermenéutica.

The concept of well-being of rural families is part of a theory under construction in which new theoretical elements are constantly being incorporated. This research aims to determine the influence of farmers’ knowledge on the well‑being of cocoa growing families in the departments of Santander, Huila, Meta and Caquetá, Colombia. Four categories of farmers were identified with different levels of knowledge in the management of cocoa cultivation obtained through a cluster analysis. The well-being of cocoa farmers, understood as the balance (...) in the capital endowment of rural households, was obtained through the application of a semi-structured interview with 49 variables of human, cultural, social, political, natural, built, and financial capitals. The results show that cocoa knowledge is heterogeneous in the study area, with a slight improvement towards harvesting, post-harvest and transformation links. There is a positive relationship between cocoa knowledge and the well-being of cocoa farming families. Thus, producers with greater integral knowledge, with emphasis on post-harvest and bean transformation links, showed greater well-being. The Random Forest analysis identified that human capital (political, social, human, and cultural) made the greatest contribution to well-being. The findings show that cocoa knowledge contributes to the well-being of rural households to the extent that it favors vertical relationships (linkages with local governments) and horizontal relationships of producers (participation of association managers, sharing knowledge with friends, neighbors and partners, and cocoa training). (shrink)

La Psicología de la Sustentabilidad (PS) estudia las problemáticas hídricas considerando la relación entre disponibilidad per cápita y consumo de agua. A partir de conceptos tales como; densidad poblacional, infraestructura hídrica y provisión de agua plantea tres estilos de vida relativos al almacenamiento de agua, la reparación de fugas y el consumo hídrico. La PS advierte que las relaciones causales entre las problemáticas hídricas y los estilos de vida son relevantes si se considera el Desarrollo Local Sustentable más que regional (...) y global. A medida que las problemáticas hídricas se intensifican, procesos actitudinales y de austeridad prevalecen sobre el dispendio de agua. En contraste, las situaciones hídricas en equilibrio con el consumo residencial facilitan el dispendio. La discusión alusiva a las problemáticas hídricas y los estilos de vida permitirá construir un sistema tarifario de consumo y delimitar las políticas públicas que se requerirán en el marco de la crisis de abastecimiento y distribución que se espera en los próximos años. (shrink)

In this paper a definition of n-valued system in the context of the algebraizable logics is proposed. We define and study the variety V3, showing that it is definitionally equivalent to the equivalent quasivariety semantics for the “Three-valued BCK-logic”. As a consequence we find an axiomatic definition of the above system.

En las ciencias cognoscitivas, existe una teoría con respecto a la arquitectura computacional de la mente conocida como el modularismo masivo. Esta teoría sostiene que la mente está en su mayoría constituida por mecanismos que son cognoscitivamente modulares. Algunos de los defensores de esta teoría proponen un argumento cuya conclusión es que es muy probable que mecanismos que son cognoscitivamente muy modulares sean más evolucionables que aquellos mecanismos que no son cognoscitivamente modulares. Aquí muestro que para poder defender plausiblemente esta (...) conclusión es necesario añadir a la noción de modularidad cognoscitiva la siguiente característica: "Un sistema cognoscitivo S de organismos de una población P es cognoscitivamente modular sólo si S es variacionalmente modular en P." Defiendo también la idea que una de las características que normalmente se asocian al concepto de modularidad cognoscitiva-i.e., la noción de doble disociación cognoscitiva-es muy cercana a la idea de modularidad variacional. Adicionalmente, argumento que no hay razones positivas, y sí algunas razones negativas, para pensar que las otras características usualmente asociadas al concepto de modularidad cognoscitiva-tales como la especificidad de dominio o la especialización funcional-coadyuven a la evolucionabilidad de los módulos cognoscitivos. In the cognitive sciences, there is a theory concerning the computational architecture of the mind known as massive modularity. This theory holds that the mind is constituted mostly by cognitive modules. Some of the defenders of this theory have put forward an argument whose conclusion is that it is very likely that those mechanisms that are cognitively very modular are more evolvable than mechanisms that are not cognitively modular. Here I show that a plausible defense of this conclusion requires us to add to the usual notion of cognitive modularity the following characteristic: "A cognitive system S of organism of a population P is cognitively modular only if S is variationally modular in P." I also defend the view that one of the characteristics normally associated to the concept of cognitive modularity-namely, the notion of a double dissociation-is conceptually close to the concept of variational modularity. Additionally, I argue that there are not positive reasons-while there are some negative ones-to think that the other characteristics usually associated to cognitive modularity, such as domain specificity or functional specialization, enhance the evolvability of cognitive modules. (shrink)

In this book Strawson is again considering topics as the existence of the exterior world, the moral attitudes, the universal... The novelty is not so in his original ideas as in the fact that these are useful to keep on completing the doctrine of a "descriptive" and "naturalist" metaphy-sick against "revisionism" such as the scepticism in its different modalities.

The origin of chordates and the consequent genesis of vertebrates were major events in natural history. The amphioxus (lancelet) is now recognised as the closest extant relative to the stem chordate and is the only living invertebrate that retains a vertebrate‐like development and body plan through its lifespan, despite more than 500 million years of independent evolution from the stem vertebrate. The inspiring data coming from its recently sequenced genome confirms that amphioxus has a prototypical chordate genome with respect to (...) gene content and structure, and even chromosomal organisation. Pushed by joint efforts of amphioxus researchers, amphioxus is now entering a new era, namely its maturation as a laboratory model, through the availability of a large amount of molecular data and the advent of experimental manipulation of the embryo. These two facts may well serve to illuminate the hidden secrets of the genetic changes that generated, among other vertebrates, ourselves. (shrink)

Sr. Rector de la Universidad BolivarianaIlustrísimas autoridadesProfesores de la UniversidadMiembros de la Comunidad universitariaRepresentantes de las organizaciones solidariasSeñoras y señoresMe siento profundamente feliz y conmovido. Feliz por haberme abierto las puertas de esta universidad y concederme esta alta distinción que no sólo culmina una amistad sino que inicia un camino de estrecha colaboración y de esperanzas entretejidas. Me honráis compañeros con vuestra acogida a este claust..

The most popular work of Francisco Sánchez, Quo nihil scitur (1581), transmits an absolutely sceptic thought. However, other writings like Carmen de Cometa anni M.D.LXXVII (1578), offer us different ideas about how Sánchez considers possible the scientific knowledge like, for example, his idea about the casual relations between natural objects.

The purpose of the present paper is to demonstrate a series of connections in terms of concepts and subjects between Ockham and Kant’s philosophical models that may provide a comprehensive framework for their respective insights on Law. Our main thesis postulates the existence of a continuum of certain fundamental assumptions derived from Nominalist theology and enlightened rationality that contribute to the essential unity of so-called “modern thought” and how such continuity is projected in the legal domain. In this sense, we (...) suggest the need to reflect upon the tacit Nominalism underlying Kantian criticism, which, although devoid of all theological premises, reconstructs metaphysics while preserving its basic scheme. In order to do so, our starting point is a very brief reference to the similarities between their respective theories of knowledge. We go on to analyze the structure behind moral actions according to Ockham and Kant’s doctrines. Finally, we point to certain founding principles and elements common to both doctrines in the field of legal-political thought. (shrink)

Luis Jiménez Moreno murió en octubre de 2007 a los 77 años de edad. Durante los últimos 30 años perteneció a la Universidad Complutense, de la que llegó a ser catedrático. Había estudiado en Salamanca, Roma, Valencia y Munich. Su tesis doctoral sobre el pensamiento antropológico de Nietzsche fue dirigida por Aranguren. Fue catedrático de instituto en Andújar, Ávila y Badalona, y profesor de universidad en Barcelona y Madrid. El presente artículo recoge los datos fundamentales de su vida, así como (...) toda su obra dividida en libros, artículos, ensayos, conferencias, ponencias y comunicaciones en congresos, seminarios, simposios, reuniones científicas, etc. (shrink)

Este artículo discute y analiza la formación del carácter crítico e intelectual en Rafael Gutiérrez Girardot. A partir de fuentes diversas y, en parte, inexploradas, se reconstruye el proceso de formación y ejercicio de su actividad crítica entre 1950 y 1965. Se tienen en cuenta tanto las relaciones con otros intelectuales como la influencia de los diversos contextos en los cuales se dieron dichas relaciones. Así, su participación en Cuadernos Hispanoamericanos, su correspondencia con Alfonso Reyes y con Nils Hedberg, su (...) actividad diplomática, su trabajo editorial y de traducción y, finalmente, su práctica docente, se estudian con objeto de tener un marco comprensivo. La obra crítica de Gutiérrez Girardot dista de estar comprendida y, de hecho, se precisa todavía de un exhaustivo trabajo de reconstrucción y análisis. This paper discusses and analyses the critical and intellectual nature of the work of Rafael Gutiérrez Girardot. It reproduces the process of construction and exercise of his critical activity (1950-1965), based on different sources some of them not yet very studied. The paper takes into account his relationships with other intellectuals and the influence of its different contexts. Thus, in order to get a comprehensive framework, it studies his participation in Cuadernos Hispanoamericanos, his correspondence with Alfonso Reyes and Nils Hedberg, his diplomatic activity, his work as editor and translator and finally his teaching experience. The critical work of Gutiérrez Girardot is far from being completely interpreted and this makes necessary an exhaustive work of reconstruction and analysis. (shrink)

El presente artículo sostiene la siguiente hipótesis: la inmensa mayoría de las conceptualizaciones teóricas con las que, a inicios del siglo XXI, se intenta dar cuenta de la subjetividad contemporánea son explícita o subrepticiamente reelaboraciones del concepto de superhombre. De ciborgs a posthumanos, pasando por una amplia y variada gama de sujetos contemporáneos, se puede apreciar que el concepto de Übermensch aporta las claves fundamentales con las cuales deconstruir el concepto de identidad fija que pone en juego el universalismo abstracto. (...) Siguiendo la teorización de Nietzsche, estas nuevas posiciones teóricas proponen una forma particular y concreta de vida como alternativa a las dicotomías y trasmundos con que la metafísica construyó a los sujetos del pasado. Sin embargo, estas propuestas han pasado por alto algo fundamental. Para demostrarlo, proponemos una relectura de Nietzsche y de dichos conceptos con el objetivo de plantear una nueva manera de pensar sobre la vida. (shrink)

Histamine is a multifunctional biogenic amine with relevant roles in intercellular communication, inflammatory processes and highly prevalent pathologies. Histamine biosynthesis depends on a single decarboxylation step, carried out by a PLP-dependent histidine decarboxylase activity (EC 4.1.1.22), an enzyme that still remains to be fully characterized. Nevertheless, during the last few years, important advances have been made in this field, including the generation and validation of the first three-dimensional model of the enzyme, which allows us to revisit previous results and conclusions. (...) This essay provides a comprehensive review of the current knowledge of the structural and functional characteristics of mammalian histidine decarboxylase. BioEssays 27:57–63, 2005. © 2004 Wiley Periodicals, Inc. (shrink)

In this article, I explore the role of the body in Indian thought through the lens of Lilian Silburn’s works, focusing on the idea of carving the cosmos, namely of somatic performances that have cosmological relevance. First, I delve into her biography, to study, subsequently, her analysis of ancient Vedic philosophy, the Brāhmaṇa, the Upanişad, and Buddhism. In this manner, I touch upon a series of conceptual developments, trying to understand the constant tensions between the discontinuous and the continuous, the (...) non-arranged and the arranged, the multiple and the One, and finally between eternalism and nihilism. I conclude by examining the way Buddhism has of resolving these tensions in the non-substantial theory of Karman. (shrink)

Leibniz endorses several tenets regarding explanation: (1) causes provide contrastive explanations of their effects, (2) the past and the future can be read from the present, and (3) primitive force and derivative forces drive and explain changes in monadic states. I argue that, contrary to initial appearances, these tenets do not preclude an intelligible conception of contingency in Leibniz’s system. In brief, an agent is free to the extent that she determines herself to do that which she deliberately judges to (...) be the best from several considered options that she could have brought about, had she come to the deliberative conclusion that these options were best. I develop a model which illustrates how Leibnizian agents could have come to different deliberative conclusions, and which thus illustrates how Leibnizian agents could have acted differently. (shrink)

El cálculo proposicional se basa proposiciones que son tautologías, antilogías y de tipo contingente, construidas con las operaciones de disyunción, conjunción, y negación, así como con el llamado condicional material para trasladar los enunciados condicionales. Con todo ello se obtiene una estructura de álgebra de Boole, que permite equiparar el cálculo proposicional al cálculo algebraico booleano. En parte, la simplificación conceptual que se obtiene resulta de ser el orden parcial del álgebra equivalente a la afirmación del condicional material. Además, con (...) tal metodología cabe ver qué partes del cálculo proposicional clásico pueden trasladarse, aun con limitaciones, a estructuras más débiles y, a la vez, más generales, como son los ortoretículos no booleanos o las álgebras de De Morgan.El cálculo proposicional trata con la deducción. Por ello, el artículo lo desarrolla a partir de un operador de consecuencias en el sentido de Tarski. Ampliado el modelo deductivo, es fácil ver otras consecuencias que las usualmente consideradas en los textos elementales; en particular, se analizan cuatro esquemas de razonamiento deductivo típicos y, entre ellos, se presta especial atención a los usuales Modus Ponens y Modus Tollens. En el caso de las estructuras algebraicas de conjuntos ‘borrosos’, ninguna es de álgebra de Boole ni siquiera de orto-retículo y sólo cabe trabajar, en algunos casos, con álgebras de De Morgan-Kleene. Por lo tanto el cálculo proposicional ‘fuzzy’ debe construirse de acuerdo con la estructura algebraica que corresponda en cada caso y una vez elegida como representación del condicional una función que verifique el Modus Ponens. (shrink)

In this introduction to the first installment of the Common Knowledge symposium on xenophilia, the editor explains the rationale of the new project, citing increases in aggressive xenophobia internationally. He comments on the intergroup-relations theorist Todd Pittinsky's argument that, since tolerance is not logically the antithesis of negative feelings toward out-groups, even long-established traditions of toleration are inadequate to prevent intergroup aggression. Pittinsky proposes that tolerance be replaced, as a principle of peacekeeping, by the encouragement of positive feelings toward out-groups, (...) and the author of this essay responds by showing how the Freudian theory of ambivalence and the history of literature on which Freud drew in constructing it support Pittinsky's viewpoint. Enemies regularly fall in love, above all in Shakespearean drama, which Freud explains by arguing that all human relations are love-hate relations. Thus, this essay suggests, it takes as much psychic energy to repress the love in what appear to be relationships of hatred as to repress the hatred in what appear to be relationships of love. There is a metaphysical component as well to this argument: the xenophobe and xenophile equally presuppose that the identity principle is applicable to society as well as to mathematics; both assume that each discrete social group is self-identical and differs from all other groups more or less radically. The main difference between –phile and –phobe is the latter's relative incapacity to live with ambivalence. Given these arguments, one must expect to find negative as well as positive motives in the etiology and conduct of xenophilia—and the first installment of the Common Knowledge symposium is said to focus on cases of xenophilia in which varieties of enmity accompany that singular and underrated variety of love. (shrink)